Three-dimensional reconstruction of in vivo blood vessels in human skin using phase-resolved optical Doppler tomography

Three-Dimensional Reconstruction of in vivo Blood Vessels in Human Skin Using Phase-Resolved Optical Doppler Tomography

Phase-resolved optical Doppler tomography (ODT) has very high sensitivity while maintaining a fast axial scanning rate, making it possible to reconstruct blood flow in three dimensions. Here we demonstrate an ODT system that employed novel signal-processing techniques to remove aliasing effects and artifacts caused by lateral scanning and target movement. The results show that these techniques ...

3 Phase - Resolved Doppler Optical Coherence Tomography

Frequency domain phase - resolved optical Doppler and Doppler variance tomography

Frequency domain phase-resolved optical Doppler tomography (ODT) was developed with Doppler variance imaging capability. It is shown that utilizing the frequency domain method, phase-resolved ODT can achieve much higher imaging speed and velocity dynamic range than the time domain method. Structural, Doppler and Doppler variance images of fluid flow through glass channels were quantified and bl...

Phase-resolved optical coherence tomography and optical Doppler tomography for imaging blood flow in human skin with fast scanning speed and high velocity sensitivity.

We have developed a novel phase-resolved optical coherence tomography (OCT) and optical Doppler tomography (ODT) system that uses phase information derived from a Hilbert transformation to image blood flow in human skin with fast scanning speed and high velocity sensitivity. Using the phase change between sequential scans to construct flow-velocity imaging, this technique decouples spatial reso...

Motion correction of in vivo three-dimensional optical coherence tomography of human skin using a fiducial marker

This paper presents a novel method based on a fiducial marker for correction of motion artifacts in 3D, in vivo, optical coherence tomography (OCT) scans of human skin and skin scars. The efficacy of this method was compared against a standard cross-correlation intensity-based registration method. With a fiducial marker adhered to the skin, OCT scans were acquired using two imaging protocols: d...